Downregulation of G2/mitotic-specific cyclinB1 triggers autophagy via AMPK-ULK1-dependent signal pathway in nasopharyngeal carcinoma cells

CyclinB1 is a regulatory protein involved in mitosis. Multiple lines of evidence indicate that cyclinB1 depletion constrains proliferation and induces apoptosis in human tumor cells. The cells become susceptible to suffer a critical situation when cyclinB1 is downregulated. Autophagy is a major intr...

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Detalles Bibliográficos
Autores principales: Xie, Xianhe, Lin, Wanzun, Zheng, Weili, Chen, Ting, Yang, Haitao, Sun, Lijun, Huang, Fei, Wang, Zili, Lin, Heng, Chen, Long, Liu, Jun, Yang, Liyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353984/
https://www.ncbi.nlm.nih.gov/pubmed/30700698
http://dx.doi.org/10.1038/s41419-019-1369-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353984/
https://www.ncbi.nlm.nih.gov/pubmed/30700698
http://dx.doi.org/10.1038/s41419-019-1369-8

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