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Network Analysis Reveals TNF as a Major Hub of Reactive Inflammation Following Spinal Cord Injury

Spinal cord injury (SCI) leads to reactive inflammation and other harmful events that limit spinal cord regeneration. We propose an approach for studying the mechanisms at the levels of network topology, gene ontology, signaling pathways, and disease inference. We treated inflammatory mediators as t...

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Detalles Bibliográficos
Autores principales: Zhu, Weiping, Chen, Xuning, Ning, Le, Jin, Kan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354014/
https://www.ncbi.nlm.nih.gov/pubmed/30700814
http://dx.doi.org/10.1038/s41598-018-37357-1