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Measurements of intrahost viral diversity require an unbiased diversity metric

Viruses exist within hosts at large population sizes and are subject to high rates of mutation. As such, viral populations exhibit considerable sequence diversity. A variety of summary statistics have been developed which describe, in a single number, the extent of diversity in a viral population; s...

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Detalles Bibliográficos
Autores principales: Zhao, Lei, Illingworth, Christopher J R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354029/
https://www.ncbi.nlm.nih.gov/pubmed/30723551
http://dx.doi.org/10.1093/ve/vey041