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Methylation Changes of Primary Tumors, Monolayer, and Spheroid Tissue Culture Environments in Malignant Melanoma and Breast Carcinoma

Epigenetic changes have major role in the normal development and programming of gene expression. Aberrant methylation results in carcinogenesis. The primary objective of our study is to determine whether primary tumor tissue and cultured tumor cells in 2D and 3D tissue culture systems have the same...

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Detalles Bibliográficos
Autores principales: Şükrüoğlu Erdoğan, Özge, Kılıç Erciyas, Seda, Bilir, Ayhan, Buğra Tunçer, Şeref, Akdeniz Ödemiş, Demet, Kurul, Sıdıka, Karanlık, Hasan, Cabıoğlu, Neslihan, Yazıcı, Hülya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354143/
https://www.ncbi.nlm.nih.gov/pubmed/30792990
http://dx.doi.org/10.1155/2019/1407167