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Synthesis and Preclinical Characterization of the PSMA-Targeted Hybrid Tracer PSMA-I&F for Nuclear and Fluorescence Imaging of Prostate Cancer

The prostate-specific membrane antigen (PSMA)–targeted radiotracers (68)Ga/(177)Lu-PSMA-I&T and (99m)Tc-PSMA-I&S (for imaging and surgery) are currently successfully used for clinical PET imaging, radionuclide therapy, and radioguided surgery of metastatic prostate cancer. To additionally ex...

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Detalles Bibliográficos
Autores principales: Schottelius, Margret, Wurzer, Alexander, Wissmiller, Katharina, Beck, Roswitha, Koch, Maximilian, Gorpas, Dimitrios, Notni, Johannes, Buckle, Tessa, van Oosterom, Matthias N., Steiger, Katja, Ntziachristos, Vasilis, Schwaiger, Markus, van Leeuwen, Fijs W.B., Wester, Hans-Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354225/
https://www.ncbi.nlm.nih.gov/pubmed/30237214
http://dx.doi.org/10.2967/jnumed.118.212720