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Exosome-mediated secretion of LOXL4 promotes hepatocellular carcinoma cell invasion and metastasis

BACKGROUND: Lysyl oxidase-like 4 (LOXL4) has been found to be dysregulated in several human malignancies, including hepatocellular carcinoma (HCC). However, the role of LOXL4 in HCC progression remains largely unclear. In this study, we investigated the clinical significance and biological involveme...

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Detalles Bibliográficos
Autores principales: Li, Rongkun, Wang, Yahui, Zhang, Xiaoxin, Feng, Mingxuan, Ma, Jun, Li, Jun, Yang, Xiaomei, Fang, Fang, Xia, Qiang, Zhang, Zhigang, Shang, Mingyi, Jiang, Shuheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354392/
https://www.ncbi.nlm.nih.gov/pubmed/30704479
http://dx.doi.org/10.1186/s12943-019-0948-8