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Resveratrol attenuates oxidative injury in human umbilical vein endothelial cells through regulating mitochondrial fusion via TyrRS-PARP1 pathway

BACKGROUND/AIMS: Oxidative stress-induced damage in endothelial cells is a crucial initiator of atherosclerosis (AS), which is highly related to excessive reactive oxygen species (ROS) and mitochondrial dynamics. Resveratrol (RSV) exerts beneficial effects against endothelial oxidative injury, while...

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Detalles Bibliográficos
Autores principales: Yang, Jining, Zhou, Xi, Zeng, Xianglong, Hu, Ou, Yi, Long, Mi, Mantian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354417/
https://www.ncbi.nlm.nih.gov/pubmed/30733817
http://dx.doi.org/10.1186/s12986-019-0338-7