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Derivation of Haploid Trophoblast Stem Cells via Conversion In Vitro

Owing to their single genome, haploid cells are powerful to uncover unknown genes by performing genetic screening in mammals. However, no haploid cell line from an extraembryonic lineage has been achieved yet, which limits the application of haploid cells in placental genetic screening. Here, we sho...

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Detalles Bibliográficos
Autores principales: Peng, Keli, Li, Xu, Wu, Congyu, Wang, Yuna, Yu, Jian, Zhang, Jinxin, Gao, Qian, Zhang, Wenhao, Zhang, Qian, Fan, Yong, Yu, Yang, Shuai, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354440/
https://www.ncbi.nlm.nih.gov/pubmed/30635215
http://dx.doi.org/10.1016/j.isci.2018.12.014