RNF216 Regulates the Migration of Immortalized GnRH Neurons by Suppressing Beclin1-Mediated Autophagy

RNF216, encoding an E3 ubiquitin ligase, has been identified as a causative gene for Gordon Holmes syndrome, characterized by ataxia, dementia, and hypogonadotropic hypogonadism. However, it is still elusive how deficiency in RNF216 leads to hypogonadotropic hypogonadism. In this study, by using GN1...

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Detalles Bibliográficos
Autores principales: Li, Fangfang, Li, Dengfeng, Liu, Huadie, Cao, Bei-Bei, Jiang, Fang, Chen, Dan-Na, Li, Jia-Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354547/
https://www.ncbi.nlm.nih.gov/pubmed/30733708
http://dx.doi.org/10.3389/fendo.2019.00012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354547/
https://www.ncbi.nlm.nih.gov/pubmed/30733708
http://dx.doi.org/10.3389/fendo.2019.00012

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