Diosmetin Attenuates Akt Signaling Pathway by Modulating Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κB)/Inducible Nitric Oxide Synthase (iNOS) in Streptozotocin (STZ)-Induced Diabetic Nephropathy Mice

BACKGROUND: We evaluated the nephroprotective effect of diosmetin in streptozotocin (STZ)-induced diabetic nephropathy (DN) mice. MATERIAL/METHODS: Diabetes was induced by injecting STZ (50 mg/kg) i.p. for 5 days. Biochemical parameters, such as fasting blood glucose, creatinine, BUN in the serum, a...

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Detalles Bibliográficos
Autores principales: Jiang, Yingsong, Liu, Jiguo, Zhou, Zemei, Liu, Ke, Liu, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Animal Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354632/
https://www.ncbi.nlm.nih.gov/pubmed/30278036
http://dx.doi.org/10.12659/MSM.910764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354632/
https://www.ncbi.nlm.nih.gov/pubmed/30278036
http://dx.doi.org/10.12659/MSM.910764

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