Cargando…

A novel mechanism of synaptic and cognitive impairments mediated via microRNA-30b in Alzheimer's disease

BACKGROUND: It is widely accepted that cognitive and memory deficits in Alzheimer's disease (AD) primarily result from synaptic failure. However, the mechanisms that underlie synaptic and cognitive dysfunction remain unclear. METHODS: We utilized molecular biology techniques, electrophysiologic...

Descripción completa

Detalles Bibliográficos
Autores principales: Song, Yunping, Hu, Mei, Zhang, Jian, Teng, Zhao-qian, Chen, Chu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354659/
https://www.ncbi.nlm.nih.gov/pubmed/30522932
http://dx.doi.org/10.1016/j.ebiom.2018.11.059