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A novel mechanism of synaptic and cognitive impairments mediated via microRNA-30b in Alzheimer's disease
BACKGROUND: It is widely accepted that cognitive and memory deficits in Alzheimer's disease (AD) primarily result from synaptic failure. However, the mechanisms that underlie synaptic and cognitive dysfunction remain unclear. METHODS: We utilized molecular biology techniques, electrophysiologic...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354659/ https://www.ncbi.nlm.nih.gov/pubmed/30522932 http://dx.doi.org/10.1016/j.ebiom.2018.11.059 |