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Detection of Concordance between Transcriptional Levels of GPCRs and Receptor-Activity-Modifying Proteins

A recent phylogenetic analysis showed global co-evolution of G protein-coupled receptors (GPCRs) and receptor-activity-modifying proteins (RAMPs) suggesting global interactions between these two protein families. Experimental validation of these findings is challenging because in humans whereas ther...

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Detalles Bibliográficos
Autores principales: Barbash, Shahar, Persson, Torbjörn, Lorenzen, Emily, Kazmi, Manija A., Huber, Thomas, Sakmar, Thomas P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354700/
https://www.ncbi.nlm.nih.gov/pubmed/30660104
http://dx.doi.org/10.1016/j.isci.2018.12.024