Mathematical Modeling Highlights the Complex Role of AKT in TRAIL-Induced Apoptosis of Colorectal Carcinoma Cells

Protein kinase B/AKT is a highly connected protein involved in a range of signaling pathways. Although it is known to regulate several proteins in the apoptotic pathway, its system-level effects remain poorly understood. We investigated the dynamic interactions between AKT and key apoptotic proteins...

Descripción completa

Detalles Bibliográficos
Autores principales: Anderson, Matthew W., Moss, Joanna J., Szalai, Robert, Lane, Jon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354781/
https://www.ncbi.nlm.nih.gov/pubmed/30690394
http://dx.doi.org/10.1016/j.isci.2019.01.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354781/
https://www.ncbi.nlm.nih.gov/pubmed/30690394
http://dx.doi.org/10.1016/j.isci.2019.01.015

Ejemplares similares