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Gene Expression Changes with Minor Effects on the Population Average Have Major Effects on the Occurrence of Cells with Extreme Protein Concentrations

The cell-to-cell heterogeneity in a bacterial population provides a rich response to environmental changes and robust survival of an isogenic population. Especially, the rare, extreme phenotypes can be important for survival under transient lethal conditions. We analyze the probability of having an...

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Detalles Bibliográficos
Autores principales: Svenningsen, Mikkel Skjoldan, Semsey, Szabolcs, Mitarai, Namiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354807/
https://www.ncbi.nlm.nih.gov/pubmed/30700510
http://dx.doi.org/10.1128/mSphere.00575-18