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GATA4 molecular screening and assessment of environmental risk factors in a Moroccan cohort with tetralogy of Fallot

BACKGROUND: Tetralogy of Fallot (TOF) is the most common cyanotic congenital heart defect (CHD) with an incidence of 1/3600 live births. This disorder was associated with mutations in the transcription factors involved in cardiogenesis, like Nk2 homeobox5 (NKX2-5), GATA binding protein4 (GATA4) and...

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Detalles Bibliográficos
Autores principales: EL Bouchikhi, Ihssane, Belhassan, Khadija, Moufid, Fatima Zohra, Houssaini, Mohammed Iraqui, Bouguenouch, Laila, Samri, Imane, Bouhrim, Mohamed, Ouldim, Karim, Atmani, Samir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Makerere Medical School 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354854/
https://www.ncbi.nlm.nih.gov/pubmed/30766556
http://dx.doi.org/10.4314/ahs.v18i4.11