Patterns of differential gene expression in a cellular model of human islet development, and relationship to type 2 diabetes predisposition

AIMS/HYPOTHESIS: Most type 2 diabetes-associated genetic variants identified via genome-wide association studies (GWASs) appear to act via the pancreatic islet. Observed defects in insulin secretion could result from an impact of these variants on islet development and/or the function of mature isle...

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Detalles Bibliográficos
Autores principales: Perez-Alcantara, Marta, Honoré, Christian, Wesolowska-Andersen, Agata, Gloyn, Anna L., McCarthy, Mark I., Hansson, Mattias, Beer, Nicola L., van de Bunt, Martijn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354904/
https://www.ncbi.nlm.nih.gov/pubmed/29675560
http://dx.doi.org/10.1007/s00125-018-4612-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354904/
https://www.ncbi.nlm.nih.gov/pubmed/29675560
http://dx.doi.org/10.1007/s00125-018-4612-4

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