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Tetrabromobisphenol A Induces MMP-9 Expression via NADPH Oxidase and the activation of ROS, MAPK, and Akt Pathways in Human Breast Cancer MCF-7 Cells

Tetrabromobisphenol A (TBBPA), the most common industrial brominated flame retardant, acts as a cytotoxic, neurotoxic, and immunotoxicant, causing inflammation and tumors. However, the mechanism of TBBPA-induced matrix metalloproteinase-9 (MMP-9) expression in human breast cancer cells is not clear....

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Detalles Bibliográficos
Autores principales: Lee, Gi Ho, Jin, Sun Woo, Kim, Se Jong, Pham, Thi Hoa, Choi, Jae Ho, Jeong, Hye Gwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society of Toxicology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354942/
https://www.ncbi.nlm.nih.gov/pubmed/30766661
http://dx.doi.org/10.5487/TR.2019.35.1.093