Context dependent roles for RB-E2F transcriptional regulation in tumor suppression

RB-E2F transcriptional control plays a key role in regulating the timing of cell cycle progression from G1 to S-phase in response to growth factor stimulation. Despite this role, it is genetically dispensable for cell cycle exit in primary fibroblasts in response to growth arrest signals. Mice engin...

Descripción completa

Detalles Bibliográficos
Autores principales: Thwaites, Michael J., Cecchini, Matthew J., Passos, Daniel T., Zakirova, Komila, Dick, Frederick A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354955/
https://www.ncbi.nlm.nih.gov/pubmed/30703085
http://dx.doi.org/10.1371/journal.pone.0203577

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354955/
https://www.ncbi.nlm.nih.gov/pubmed/30703085
http://dx.doi.org/10.1371/journal.pone.0203577

Ejemplares similares