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A PRRSV GP5-Mosaic vaccine: Protection of pigs from challenge and ex vivo detection of IFNγ responses against several genotype 2 strains

Porcine reproductive and respiratory syndrome virus (PRRSV), is a highly mutable RNA virus that affects swine worldwide and its control is very challenging due to its formidable heterogeneity in the field. In the present study, DNA vaccines constructed with PRRSV GP5-Mosaic sequences were complexed...

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Detalles Bibliográficos
Autores principales: Cui, Junru, O’Connell, Caitlin M., Costa, Antonio, Pan, Yan, Smyth, Joan A., Verardi, Paulo H., Burgess, Diane J., Van Kruiningen, Herbert J., Garmendia, Antonio E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354972/
https://www.ncbi.nlm.nih.gov/pubmed/30703122
http://dx.doi.org/10.1371/journal.pone.0208801