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Nitrogen gas produces less behavioural and neurophysiological excitation than carbon dioxide in mice undergoing euthanasia

Carbon dioxide (CO(2)) is one of the most commonly used gas euthanasia agents in mice, despite reports of aversion and nociception. Inert gases such as nitrogen (N(2)) may be a viable alternative to carbon dioxide. Here we compared behavioural and electrophysiological reactions to CO(2) or N(2) at e...

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Detalles Bibliográficos
Autores principales: Detotto, Carlotta, Isler, Sarah, Wehrle, Martin, Vyssotski, Alexei L., Bettschart-Wolfensberger, Regula, Gent, Thomas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354991/
https://www.ncbi.nlm.nih.gov/pubmed/30703117
http://dx.doi.org/10.1371/journal.pone.0210818