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Nitrogen gas produces less behavioural and neurophysiological excitation than carbon dioxide in mice undergoing euthanasia
Carbon dioxide (CO(2)) is one of the most commonly used gas euthanasia agents in mice, despite reports of aversion and nociception. Inert gases such as nitrogen (N(2)) may be a viable alternative to carbon dioxide. Here we compared behavioural and electrophysiological reactions to CO(2) or N(2) at e...
Autores principales: | Detotto, Carlotta, Isler, Sarah, Wehrle, Martin, Vyssotski, Alexei L., Bettschart-Wolfensberger, Regula, Gent, Thomas C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354991/ https://www.ncbi.nlm.nih.gov/pubmed/30703117 http://dx.doi.org/10.1371/journal.pone.0210818 |
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