Structure of the DP1–DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases

PolD is an archaeal replicative DNA polymerase (DNAP) made of a proofreading exonuclease subunit (DP1) and a larger polymerase catalytic subunit (DP2). Recently, we reported the individual crystal structures of the DP1 and DP2 catalytic cores, thereby revealing that PolD is an atypical DNAP that has...

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Detalles Bibliográficos
Autores principales: Raia, Pierre, Carroni, Marta, Henry, Etienne, Pehau-Arnaudet, Gérard, Brûlé, Sébastien, Béguin, Pierre, Henneke, Ghislaine, Lindahl, Erik, Delarue, Marc, Sauguet, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355029/
https://www.ncbi.nlm.nih.gov/pubmed/30657780
http://dx.doi.org/10.1371/journal.pbio.3000122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355029/
https://www.ncbi.nlm.nih.gov/pubmed/30657780
http://dx.doi.org/10.1371/journal.pbio.3000122

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