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Structure of the DP1–DP2 PolD complex bound with DNA and its implications for the evolutionary history of DNA and RNA polymerases
PolD is an archaeal replicative DNA polymerase (DNAP) made of a proofreading exonuclease subunit (DP1) and a larger polymerase catalytic subunit (DP2). Recently, we reported the individual crystal structures of the DP1 and DP2 catalytic cores, thereby revealing that PolD is an atypical DNAP that has...
Autores principales: | Raia, Pierre, Carroni, Marta, Henry, Etienne, Pehau-Arnaudet, Gérard, Brûlé, Sébastien, Béguin, Pierre, Henneke, Ghislaine, Lindahl, Erik, Delarue, Marc, Sauguet, Ludovic |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355029/ https://www.ncbi.nlm.nih.gov/pubmed/30657780 http://dx.doi.org/10.1371/journal.pbio.3000122 |
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