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Chemotherapy-generated cell debris stimulates colon carcinoma tumor growth via osteopontin

Colon cancer recurrence after therapy, such as 5-fluorouracil (5-FU), remains a challenge in the clinical setting. Chemotherapy reduces tumor burden by inducing cell death; however, the resulting dead tumor cells, or debris, may paradoxically stimulate angiogenesis, inflammation, and tumor growth. H...

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Detalles Bibliográficos
Autores principales: Chang, Jaimie, Bhasin, Swati S., Bielenberg, Diane R., Sukhatme, Vikas P., Bhasin, Manoj, Huang, Sui, Kieran, Mark W., Panigrahy, Dipak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355061/
https://www.ncbi.nlm.nih.gov/pubmed/29957058
http://dx.doi.org/10.1096/fj.201800019RR