A young testicular microenvironment protects Leydig cells against age-related dysfunction in a mouse model of premature aging

Testicular Leydig cells (LCs) are the primary source of circulating androgen in men. As men age, circulating androgen levels decline. However, whether reduced LC steroidogenesis results from specific effects of aging within LCs or reflects degenerative alterations to the wider supporting microenviro...

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Detalles Bibliográficos
Autores principales: Curley, Michael, Milne, Laura, Smith, Sarah, Jørgensen, Anne, Frederiksen, Hanne, Hadoke, Patrick, Potter, Paul, Smith, Lee B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355079/
https://www.ncbi.nlm.nih.gov/pubmed/30080443
http://dx.doi.org/10.1096/fj.201800612R

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355079/
https://www.ncbi.nlm.nih.gov/pubmed/30080443
http://dx.doi.org/10.1096/fj.201800612R

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