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Understanding the coupling between DNA damage detection and UvrA’s ATPase using bulk and single molecule kinetics

Nucleotide excision repair (NER) protects cells against diverse types of DNA damage, principally UV irradiation. In Escherichia coli, damage is recognized by 2 key enzymes: UvrA and UvrB. Despite extensive investigation, the role of UvrA’s 2 ATPase domains in NER remains elusive. Combining single-mo...

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Detalles Bibliográficos
Autores principales:	Barnett, Jamie T., Kad, Neil M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Federation of American Societies for Experimental Biology 2019
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355085/ https://www.ncbi.nlm.nih.gov/pubmed/30020831 http://dx.doi.org/10.1096/fj.201800899R

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