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Increased PD-L1 expression in radioresistant HNSCC cell lines after irradiation affects cell proliferation due to inactivation of GSK-3beta

At present, targeting PD-1/PD-L1 axis for immune checkpoint inhibition has improved treatment of various tumor entities, including head and neck squamous cell carcinoma (HNSCC). However, one part of the patient cohort still shows little improvement or even hyperprogression. We established three radi...

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Detalles Bibliográficos
Autores principales: Schulz, Daniela, Stancev, Irene, Sorrentino, Antonio, Menevse, Ayse-Nur, Beckhove, Philipp, Brockhoff, Gero, Hautmann, Matthias Günther, Reichert, Torsten Erich, Bauer, Richard Josef, Ettl, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355177/
https://www.ncbi.nlm.nih.gov/pubmed/30728908
http://dx.doi.org/10.18632/oncotarget.26542