Inhibition of 5-lipoxygenase downregulates stemness and kills prostate cancer stem cells by triggering apoptosis via activation of c-Jun N-terminal kinase

The cancer stem cell (CSC) concept suggests that neoplastic clones are maintained exclusively by a rare group of cells possessed with stem cell properties. CSCs are characterized by features that include self-renewal, pluripotency and tumorigenicity, and are thought to be solely responsible for tumo...

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Detalles Bibliográficos
Autores principales: Sarveswaran, Sivalokanathan, Varma, Nadimpalli R.S., Morisetty, Shravan, Ghosh, Jagadananda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355185/
https://www.ncbi.nlm.nih.gov/pubmed/30728896
http://dx.doi.org/10.18632/oncotarget.13422

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355185/
https://www.ncbi.nlm.nih.gov/pubmed/30728896
http://dx.doi.org/10.18632/oncotarget.13422

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