Imbalanced sphingolipid signaling is maintained as a core proponent of a cancerous phenotype in spite of metabolic pressure and epigenetic drift

Tumor heterogeneity may arise through genetic drift and environmentally driven clonal selection for metabolic fitness. This would promote subpopulations derived from single cancer cells that exhibit distinct phenotypes while conserving vital pro-survival pathways. We aimed to identify significant dr...

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Detalles Bibliográficos
Autores principales: Speirs, Monique M.P., Swensen, Adam C., Chan, Tsz Y., Jones, Peter M., Holman, John C., Harris, McCall B., Maschek, John A., Cox, James E., Carson, Richard H., Hill, Jonathon T., Andersen, Joshua L., Prince, John T., Price, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355186/
https://www.ncbi.nlm.nih.gov/pubmed/30728898
http://dx.doi.org/10.18632/oncotarget.26533

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355186/
https://www.ncbi.nlm.nih.gov/pubmed/30728898
http://dx.doi.org/10.18632/oncotarget.26533

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