A structural model of the immune checkpoint CD160–HVEM complex derived from HDX-mass spectrometry and molecular modeling

CD160 is a T cell coinhibitory molecule that interacts with the herpes virus entry mediator (HVEM) on antigen-presenting cells to provide an inhibitory signal to T cells. To date, the structure of CD160 and its complex with HVEM are unknown. Here, we have identified the fragments of CD160 interactin...

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Detalles Bibliográficos
Autores principales: Kuncewicz, Katarzyna, Spodzieja, Marta, Sieradzan, Adam, Karczyńska, Agnieszka, Dąbrowska, Katarzyna, Dadlez, Michał, Speiser, Daniel E., Derre, Laurent, Rodziewicz-Motowidło, Sylwia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355189/
https://www.ncbi.nlm.nih.gov/pubmed/30728903
http://dx.doi.org/10.18632/oncotarget.26570

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355189/
https://www.ncbi.nlm.nih.gov/pubmed/30728903
http://dx.doi.org/10.18632/oncotarget.26570

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