Programmed knockout mutation of liver fluke granulin attenuates virulence of infection-induced hepatobiliary morbidity

Infection with the food-borne liver fluke Opisthorchis viverrini is the principal risk factor (IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, 2012) for cholangiocarcinoma (CCA) in the Lower Mekong River Basin countries including Thailand, Lao PDR, Vietnam and Cambodia. We expl...

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Detalles Bibliográficos
Autores principales: Arunsan, Patpicha, Ittiprasert, Wannaporn, Smout, Michael J, Cochran, Christina J, Mann, Victoria H, Chaiyadet, Sujittra, Karinshak, Shannon E, Sripa, Banchob, Young, Neil David, Sotillo, Javier, Loukas, Alex, Brindley, Paul J, Laha, Thewarach
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Microbiology and Infectious Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355195/
https://www.ncbi.nlm.nih.gov/pubmed/30644359
http://dx.doi.org/10.7554/eLife.41463

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355195/
https://www.ncbi.nlm.nih.gov/pubmed/30644359
http://dx.doi.org/10.7554/eLife.41463

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