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Silymarin-laden PVP-PEG polymeric composite for enhanced aqueous solubility and dissolution rate: Preparation and in vitro characterization

The aim of this work was to develop, optimize and characterize a silymarin-laden polyvinylpyrrolidone (PVP)-polyethylene glycol (PEG) polymeric composite to resolve low aqueous solubility and dissolution rate problem of the drug. A number of silymarin-laden polymeric formulations were fabricated wit...

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Detalles Bibliográficos
Autores principales: Yousaf, Abid Mehmood, Malik, Usman Rashid, Shahzad, Yasser, Mahmood, Tariq, Hussain, Talib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Xi'an Jiaotong University 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355470/
https://www.ncbi.nlm.nih.gov/pubmed/30740255
http://dx.doi.org/10.1016/j.jpha.2018.09.003