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A novel deep targeted sequencing method for minimal residual disease monitoring in acute myeloid leukemia

A high proportion of patients with acute myeloid leukemia who achieve minimal residual disease negative status ultimately relapse because a fraction of pathological clones remains undetected by standard methods. We designed and validated a high-throughput sequencing method for minimal residual disea...

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Detalles Bibliográficos
Autores principales: Onecha, Esther, Linares, Maria, Rapado, Inmaculada, Ruiz-Heredia, Yanira, Martinez-Sanchez, Pilar, Cedena, Teresa, Pratcorona, Marta, Oteyza, Jaime Perez, Herrera, Pilar, Barragan, Eva, Montesinos, Pau, Vela, Jose Antonio Garcia, Magro, Elena, Anguita, Eduardo, Figuera, Angela, Riaza, Rosalia, Martinez-Barranco, Pilar, Sanchez-Vega, Beatriz, Nomdedeu, Josep, Gallardo, Miguel, Martinez-Lopez, Joaquin, Ayala, Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355493/
https://www.ncbi.nlm.nih.gov/pubmed/30093399
http://dx.doi.org/10.3324/haematol.2018.194712