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Rheb1 loss leads to increased hematopoietic stem cell proliferation and myeloid-biased differentiation in vivo
Hematopoietic stem cells constitute a unique subpopulation of blood cells that can give rise to all types of mature cells in response to physiological demands. However, the intrinsic molecular machinery that regulates this transformative property remains elusive. In this paper, we demonstrate that s...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ferrata Storti Foundation
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355497/ https://www.ncbi.nlm.nih.gov/pubmed/30262562 http://dx.doi.org/10.3324/haematol.2018.194811 |