Rheb1 loss leads to increased hematopoietic stem cell proliferation and myeloid-biased differentiation in vivo

Hematopoietic stem cells constitute a unique subpopulation of blood cells that can give rise to all types of mature cells in response to physiological demands. However, the intrinsic molecular machinery that regulates this transformative property remains elusive. In this paper, we demonstrate that s...

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Detalles Bibliográficos
Autores principales: Wang, Xiaomin, Gao, Yanan, Gao, Juan, Li, Minghao, Zhou, Mi, Wang, Jinhong, Pang, Yakun, Cheng, Hui, Yuan, Chase, Chu, Yajing, Jiang, Yu, Zhou, Jianfeng, Luo, Hongbo R., Ju, Zhenyu, Cheng, Tao, Yuan, Weiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355497/
https://www.ncbi.nlm.nih.gov/pubmed/30262562
http://dx.doi.org/10.3324/haematol.2018.194811

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