The TLR7 ligand R848 prevents mouse graft-versus-host disease and cooperates with anti-interleukin-27 antibody for maximal protection and regulatory T-cell upregulation

In spite of considerable therapeutic progress, acute graft-versus-host disease still limits allogeneic hematopoietic cell transplantation. We recently reported that mouse infection with nidovirus lactate dehydrogenase elevating virus impairs disease in non-conditioned B6D2F1 recipients of parental B...

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Detalles Bibliográficos
Autores principales: Gaignage, Mélanie, Marillier, Reece G., Cochez, Perrine M., Dumoutier, Laure, Uyttenhove, Catherine, Coutelier, Jean-Paul, Van Snick, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ferrata Storti Foundation 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355498/
https://www.ncbi.nlm.nih.gov/pubmed/30213828
http://dx.doi.org/10.3324/haematol.2018.195628

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355498/
https://www.ncbi.nlm.nih.gov/pubmed/30213828
http://dx.doi.org/10.3324/haematol.2018.195628

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