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The TLR7 ligand R848 prevents mouse graft-versus-host disease and cooperates with anti-interleukin-27 antibody for maximal protection and regulatory T-cell upregulation

In spite of considerable therapeutic progress, acute graft-versus-host disease still limits allogeneic hematopoietic cell transplantation. We recently reported that mouse infection with nidovirus lactate dehydrogenase elevating virus impairs disease in non-conditioned B6D2F1 recipients of parental B...

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Detalles Bibliográficos
Autores principales:	Gaignage, Mélanie, Marillier, Reece G., Cochez, Perrine M., Dumoutier, Laure, Uyttenhove, Catherine, Coutelier, Jean-Paul, Van Snick, Jacques
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ferrata Storti Foundation 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355498/ https://www.ncbi.nlm.nih.gov/pubmed/30213828 http://dx.doi.org/10.3324/haematol.2018.195628

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