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Usefulness of Serial Blood Sampling and PCR Replicates for Treatment Monitoring of Patients with Chronic Chagas Disease

This work evaluated a serial blood sampling procedure to enhance the sensitivity of duplex real-time quantitative PCR (qPCR) for baseline detection and quantification of parasitic loads and posttreatment identification of failure in the context of clinical trials for treatment of chronic Chagas dise...

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Detalles Bibliográficos
Autores principales: Parrado, Rudy, Ramirez, Juan Carlos, de la Barra, Anabelle, Alonso-Vega, Cristina, Juiz, Natalia, Ortiz, Lourdes, Illanes, Daniel, Torrico, Faustino, Gascon, Joaquim, Alves, Fabiana, Flevaud, Laurence, Garcia, Lineth, Schijman, Alejandro G., Ribeiro, Isabela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355557/
https://www.ncbi.nlm.nih.gov/pubmed/30509941
http://dx.doi.org/10.1128/AAC.01191-18