Host Cell Metabolism Contributes to Delayed-Death Kinetics of Apicoplast Inhibitors in Toxoplasma gondii

Toxoplasma gondii and related human parasites contain an essential plastid organelle called the apicoplast. Clinically used antibiotics and other inhibitors that disrupt apicoplast biogenesis cause a mysterious “delayed-death” phenotype in which parasite growth is unaffected during the first lytic c...

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Detalles Bibliográficos
Autores principales: Amberg-Johnson, Katherine, Yeh, Ellen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Mechanisms of Action: Physiological Effects
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355570/
https://www.ncbi.nlm.nih.gov/pubmed/30455243
http://dx.doi.org/10.1128/AAC.01646-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355570/
https://www.ncbi.nlm.nih.gov/pubmed/30455243
http://dx.doi.org/10.1128/AAC.01646-18

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