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APX001 and Other Gwt1 Inhibitor Prodrugs Are Effective in Experimental Coccidioides immitis Pneumonia

Coccidioidomycosis is a systemic fungal infection caused by the inhalation of the arthroconidia of either of two closely related dimorphic fungi, Coccidioides immitis and C. posadasii, that are endemic in the southwestern United States and other areas in the Western Hemisphere. Chronic cavitary pulm...

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Detalles Bibliográficos
Autores principales: Viriyakosol, Suganya, Kapoor, Mili, Okamoto, Sharon, Covel, Jonathan, Soltow, Quinlyn A., Trzoss, Michael, Shaw, Karen Joy, Fierer, Joshua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355600/
https://www.ncbi.nlm.nih.gov/pubmed/30455238
http://dx.doi.org/10.1128/AAC.01715-18