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Global Gene Knockout of Kcnip3 Enhances Pain Sensitivity and Exacerbates Negative Emotions in Rats

The Ca(2+)-binding protein Kv channel interacting protein 3 (KChIP3) or downstream regulatory element antagonist modulator (DREAM), a member of the neuronal calcium sensor (NCS) family, shows remarkable multifunctional properties. It acts as a transcriptional repressor in the nucleus and a modulator...

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Detalles Bibliográficos
Autores principales: Guo, Yu-Peng, Zhi, Yu-Ru, Liu, Ting-Ting, Wang, Yun, Zhang, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355686/
https://www.ncbi.nlm.nih.gov/pubmed/30740043
http://dx.doi.org/10.3389/fnmol.2019.00005