Reversion of in vivo fibrogenesis by novel chromone scaffolds

BACKGROUND: Myofibroblasts are known to play a key role in the development of idiopathic pulmonary fibrosis (IPF). Two drugs, pirfenidone and nintedanib, are the only approved therapeutic options for IPF, but their applications are limited due to their side effects. Thus, curative IPF drugs represen...

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Detalles Bibliográficos
Autores principales: Kim, Han-Soo, Yoon, Young-Min, Meang, Moon Kee, Park, Yae Eun, Lee, Ji Yong, Lee, Tae Hee, Lee, Ji Eun, Kim, Ik-Hwan, Youn, Byung-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355727/
https://www.ncbi.nlm.nih.gov/pubmed/30611717
http://dx.doi.org/10.1016/j.ebiom.2018.12.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355727/
https://www.ncbi.nlm.nih.gov/pubmed/30611717
http://dx.doi.org/10.1016/j.ebiom.2018.12.017

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