Somatic mutation detection and classification through probabilistic integration of clonal population information

Somatic mutations are a primary contributor to malignancy in human cells. Accurate detection of mutations is needed to define the clonal composition of tumours whereby clones may have distinct phenotypic properties. Although analysis of mutations over multiple tumour samples from the same patient ha...

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Detalles Bibliográficos
Autores principales: Dorri, Fatemeh, Jewell, Sean, Bouchard-Côté, Alexandre, Shah, Sohrab P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355807/
https://www.ncbi.nlm.nih.gov/pubmed/30729182
http://dx.doi.org/10.1038/s42003-019-0291-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355807/
https://www.ncbi.nlm.nih.gov/pubmed/30729182
http://dx.doi.org/10.1038/s42003-019-0291-z

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