Complement factor H regulates retinal development and its absence may establish a footprint for age related macular degeneration

Age related macular degeneration (AMD) is the most common blinding disease in those over 60 years. In 50% of cases it is associated with polymorphisms of complement factor H (FH), implicating immune vulnerability. But such individuals may exhibit abnormal outer retinal blood flow decades before dise...

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Detalles Bibliográficos
Autores principales: Sivapathasuntharam, Chrishne, Hayes, Matthew John, Shinhmar, Harpreet, Kam, Jaimie Hoh, Sivaprasad, Sobha, Jeffery, Glen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355813/
https://www.ncbi.nlm.nih.gov/pubmed/30705315
http://dx.doi.org/10.1038/s41598-018-37673-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355813/
https://www.ncbi.nlm.nih.gov/pubmed/30705315
http://dx.doi.org/10.1038/s41598-018-37673-6

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