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Small changes in synaptic gain lead to seizure-like activity in neuronal network at criticality
Epilepsy is a neurological disorder characterised by spontaneous recurrent seizures. The mechanisms by which multiple molecular and cellular changes lead to seizures is not well understood. Here, we study cortical seizure generation by simulating the activity of neuron groups in a network using the...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355815/ https://www.ncbi.nlm.nih.gov/pubmed/30705357 http://dx.doi.org/10.1038/s41598-018-37646-9 |