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Identification of a natural inhibitor of methionine adenosyltransferase 2A regulating one-carbon metabolism in keratinocytes

BACKGROUND: Psoriasis is a common chronic inflammatory skin disease which lacks effective strategies for the treatment. Natural compounds with biological activities are good tools to identify new targets with therapeutic potentials. Acetyl-11-keto-β-boswellic acid (AKBA) is the most bioactive ingred...

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Detalles Bibliográficos
Autores principales: Bai, Jing, Gao, Yuanyuan, Chen, Linjiao, Yin, Qianqian, Lou, Fangzhou, Wang, Zhikai, Xu, Zhenyao, Zhou, Hong, Li, Qun, Cai, Wei, Sun, Yang, Niu, Liman, Wang, Hong, Wei, Zhenquan, Lu, Shaoyong, Zhou, Aiwu, Zhang, Jian, Wang, Honglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355826/
https://www.ncbi.nlm.nih.gov/pubmed/30591370
http://dx.doi.org/10.1016/j.ebiom.2018.12.036