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Siglec genes confer resistance to systemic lupus erythematosus in humans and mice

A recent meta-analysis revealed the contribution of the SIGLEC6 locus to the risk of developing systemic lupus erythematosus (SLE). However, no specific Siglec (sialic acid-binding immunoglobulin-like lectin) genes (Siglecs) have been implicated in the pathogenesis of SLE. Here, we performed in sili...

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Detalles Bibliográficos
Autores principales: Flores, Rhonda, Zhang, Peng, Wu, Wei, Wang, Xu, Ye, Peiying, Zheng, Pan, Liu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355849/
https://www.ncbi.nlm.nih.gov/pubmed/29503442
http://dx.doi.org/10.1038/cmi.2017.160