Transcriptome Analysis of Mesenchymal Stem Cells from Multiple Myeloma Patients Reveals Downregulation of Genes Involved in Cell Cycle Progression, Immune Response, and Bone Metabolism

A growing body of evidence suggests a key role of tumor microenvironment, especially for bone marrow mesenchymal stem cells (MSC), in the maintenance and progression of multiple myeloma (MM), through direct and indirect interactions with tumor plasma cells. Thus, this study aimed to investigate the...

Descripción completa

Detalles Bibliográficos
Autores principales: Fernando, Rodrigo Carlini, Mazzotti, Diego Robles, Azevedo, Hatylas, Sandes, Alex Freire, Rizzatti, Edgar Gil, de Oliveira, Mariana Bleker, Alves, Veruska Lia Fook, Eugênio, Angela Isabel Pereira, de Carvalho, Fabrício, Dalboni, Maria Aparecida, Martins, David Correa, Colleoni, Gisele Wally Braga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355867/
https://www.ncbi.nlm.nih.gov/pubmed/30705326
http://dx.doi.org/10.1038/s41598-018-38314-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355867/
https://www.ncbi.nlm.nih.gov/pubmed/30705326
http://dx.doi.org/10.1038/s41598-018-38314-8

Ejemplares similares