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Disruption of mTOR and MAPK pathways correlates with severity in idiopathic autism

The molecular signature underlying autism spectrum disorder remains largely unknown. This study identifies differential expression of mTOR and MAPK pathways in patients affected by mild and severe idiopathic autism. A total of 55 subjects were enrolled, of which 22 were typically developing individu...

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Detalles Bibliográficos
Autores principales: Rosina, Eleonora, Battan, Barbara, Siracusano, Martina, Di Criscio, Lorena, Hollis, Fiona, Pacini, Laura, Curatolo, Paolo, Bagni, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355879/
https://www.ncbi.nlm.nih.gov/pubmed/30705255
http://dx.doi.org/10.1038/s41398-018-0335-z