Clostridium perfringens α-toxin impairs granulocyte colony-stimulating factor receptor-mediated granulocyte production while triggering septic shock

During bacterial infection, granulocyte colony-stimulating factor (G-CSF) is produced and accelerates neutrophil production from their progenitors. This process, termed granulopoiesis, strengthens host defense, but Clostridium perfringens α-toxin impairs granulopoiesis via an unknown mechanism. Here...

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Detalles Bibliográficos
Autores principales: Takehara, Masaya, Seike, Soshi, Sonobe, Yuuta, Bandou, Hiroto, Yokoyama, Saki, Takagishi, Teruhisa, Miyamoto, Kazuaki, Kobayashi, Keiko, Nagahama, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355902/
https://www.ncbi.nlm.nih.gov/pubmed/30729183
http://dx.doi.org/10.1038/s42003-019-0280-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355902/
https://www.ncbi.nlm.nih.gov/pubmed/30729183
http://dx.doi.org/10.1038/s42003-019-0280-2

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